PROGETTO GENETICA

Progetto FRRB 4980634 - Evaluation of genetic-molecular causes of Out-ofHospital Cardiac Arrest: from patients to families (GENETICA)

Dati del progetto

Principal Investigator

Dr. Enrico Baldi

Ente ospitante

Fondazione IRCCS Policlinico San Matteo

Area Tematica

Cardiologia

Data di inizio Progetto

16/01/2025

Data di fine Progetto

15/01/2028

Importo assegnato

 500.000,00 €

Tipo Progetto

Individuale

PROJECT AIMS

The aims are to define the exact prevalence of hereditary heart diseases in out-of-hospital cardiac arrest (OHCA) patients taking also into account gender, patient and OHCA characteristics, provincial settings and environmental pollution; to stratify the individualized arrhythmic risk of proband's family members to prevent further sudden cardiac deaths; to refine the classification of the variants of uncertain significance (VUS) on genes which can have the capability to drive to molecular alterations leading to arrhythmogenic hereditary heart diseases.