PROGETTO MULTIFSGS

Progetto FRRB ID 4972567 Multitarget therapy for primary podocytopathies with focal segmental glomerulosclerosis (MULTIFSGS)

Dati del progetto

Principal Investigator

Dr. Manuel Alfredo Podestà

Ente ospitante

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Area Tematica

Malattie Rare

Data di inizio Progetto

16/12/2024

Data di fine Progetto

15/12/2027

Importo assegnato

500.000,00 €

Tipo Progetto

Individuale

PROJECT AIM

Primary FSGS is a rare disease characterized by nephrotic syndrome and progressive loss of kidney function in half of patients despite treatment. FSGS is caused by an ill-defined, immune-related permeability factor that induces podocyte damage and glomerular scarring. The goal of this project is to determine whether therapeutic multi-targeting may prevent kidney damage in primary FSGS.