Progetto FRRB ID 4972567 Multitarget therapy for primary podocytopathies with focal segmental glomerulosclerosis (MULTIFSGS)
Dati del progetto
Principal Investigator |
Dr. Manuel Alfredo Podestà |
Ente ospitante |
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico |
Area Tematica |
Malattie Rare |
Data di inizio Progetto |
16/12/2024 |
Data di fine Progetto |
15/12/2027 |
Importo assegnato |
500.000,00 € |
Tipo Progetto |
Individuale |
PROJECT AIM
Primary FSGS is a rare disease characterized by nephrotic syndrome and progressive loss of kidney function in half of patients despite treatment. FSGS is caused by an ill-defined, immune-related permeability factor that induces podocyte damage and glomerular scarring. The goal of this project is to determine whether therapeutic multi-targeting may prevent kidney damage in primary FSGS.